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Spécifications
- Antibody type:Primary
- Antigen name:Transporter 1, ATP Binding Cassette Subfamily B member
- Clonality:Polyclonal
- Gene ID:6890
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TAP1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:50 μl
- Western blot:Yes
- Antigen synonyms:ABC17|RING4|PSF1|FLJ41500|ABCB2|TAP1*0102N|TAP1N|D6S114E|DAAP-57C1.5|APT1|FLJ26666
- Storage buffer:Preservative: NoneConstituents: Whole Serum
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Immunogen:Synthetic peptide: AKLVQRQMLGLQPA, corresponding to amino acids 735-748 of Human TAP1.
- Tested applications:ICC/IF, IP, WB
- Purification:Whole antiserum
- Cat. no.:89359-714
- Supplier No.:GTX13516
Spécifications
A propos de cet article
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
ICC: Use at an assay dependent dilution. IP: Use at a dilution of 1/100. WB: Use at a dilution of 1/4000. Detects a band of approximately 70 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: TAP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human