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Spécifications
- Antibody type:Primary
- Antigen name:Lymphoid Enhancer-Binding Factor 1
- Clonality:Monoclonal
- Clone:REMB1
- Gene ID:51176
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:LEF1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:50 μg
- Western blot:Yes
- Antigen synonyms:TCF1ALPHA|TCF1-alpha|DKFZp586H0919|LEF-1|LEF1
- Storage buffer:0.01M PBS. pH 7.5 containing 0.08% Sodium Azide
- Storage temperature:Aliquot and store at –20 °C or –80 °C. Avoid repeated freeze / thaw cycles.
- Concentration:1 mg/ml
- Immunogen:Recombinant full length LEF1 (Human).
- Tested applications:ICC/IF, WB
- Purification:Protein G purified
- Cat. no.:89359-120
- Supplier No.:GTX12034
Spécifications
A propos de cet article
Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
IF: Use at an assay dependent dilution. WB: Use at a concentration of 1 - 5 ?g/ml, this is recommended using whole extracts of human Jurkat cells or transiently expressed human LEF1 in whole cell lysates from Cos-1 cells. Predicted MW 55-57 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: LEF1
Clonality: Monoclonal
Clone: REMB1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human