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Spécifications
- Description:QuantiFluo™ Urokinase inhibitor screening assay kit
- Size:100 tests
- Cat. no.:77441-672
Spécifications
A propos de cet article
For evaluation of drugs and screening potential inhibitors of urokinase.
- Safe
- Non-radioactive assay
- Fast
- Assay is completed within a 30 minutes reaction time
- Homogeneous 'mix-incubate-measure' type assay
- Can be readily automated to assay thousands of samples per day
UROKINASE PLASMINOGEN ACTIVATOR (urokinase, uPA) is a key serine protease involved in the degradation of the extracellular matrix that catalyzes the conversion of plasminogen to active plasmin. It acts as a thrombolytic agent to break up blood clots and when over-expressed, has been reported to influence the growth of certain malignant tumors (breast, prostate, etc.). BioAssay Systems’ DUKI-100 Kit provides a convenient fluorimetric means to screen for potential urokinase inhibitors. In this assay, the fluorimetric substrate reacts with urokinase and an inhibitor will decrease the fluorescence at λex/em = 380/450 nm.