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Anti-Klrb1 Rabbit Polyclonal Antibody
Anti-Klrb1 Rabbit Polyclonal Antibody
# de catalogue 77439-386
Fournisseur:  Bioss
New Product
Anti-Klrb1 Rabbit Polyclonal Antibody
# de catalogue 77439-386
Fournisseur:  Bioss
New Product
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Spécifications

  • Antibody type:
    Primary
  • Antigen name:
    Klrb1
  • Clonality:
    Polyclonal
  • Gene ID:
    362443
  • Host:
    Rabbit
  • Isotype:
    IgG (H, L)
  • Reactivity:
    Human
  • Conjugation:
    Unconjugated
  • Size:
    100 µl
  • Western blot:
    Yes
  • Storage buffer:
    0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
  • Molecular weight:
    70
  • Storage temperature:
    Shipped at 4 ℃. Store at −20 °C for one year. Avoid repeated freeze/thaw cycles.
  • Concentration:
    1 µg/µl
  • Purification:
    Purified by protein A
  • Packaging:
    Vial

Spécifications

A propos de cet article

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.

Type: Primary
Antigen: Klrb1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human

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