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PolyHunter agarose was developed for the depletion of synthetic polymers used in solubilization steps.
Solubilization of membrane protein using synthetic copolymer nanodiscs has many advantages over traditional membrane protein solubilization methods.
Cube Biotech's PolyHunter agarose resins and MagBeads solve one of the few remaining issues with this product. After solubilization, some remaining free copolymer molecules can interfere with the subsequent affinity chromatography. Our PolyHunter products can deplete up to 99% of these interfering copolymer molecules from your solubilize.
PolyHunter agarose resin is compatible with all nanodisc copolymers that CubeBiotech offers. Therefore it is ideally suited to be purchased in conjunction with our synthetic nanodisc screening kit maxi.
Note: PolyHunter products are also available as magnetic beads and can be reused up to five times. The corresponding regeneration procedure can be found in the matching protocol PDF files.
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