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Specifications
- Antigen name:Secukinumab
- Clonality:Monoclonal
- Clone:23E11
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Size:40 μg
- Concentration:Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml
- Immunogen:Secukinumab
- Storage buffer:This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide
- Storage temperature:The lyophilized product remains stable up to 1 year at −20 °C from date of receipt. Upon reconstitution, it can be stored for 2 - 3 weeks at 2 - 8 °C or for up to 12 months at −20 °C or below. Avoid repeated freezing and thawing cycles
- Form:Lyophilized
- Cross adsorption:No
- Cat. no.:77007-524
- Packaging:Vial
Specifications
About this item
Secukinumab with brand name Cosentyx, is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is marketed by novartis for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells. IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor. Anti-Secukinumab antibody (23E11), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Secukinumab.
- High specificity
- High affinity
- High stability
GenScript has developed a broad range of off-the-shelf anti-idiotype antibodies against blockbuster drugs to help accelerate your research of biosimilars.
Type:
Antigen: Secukinumab
Clonality: Monoclonal
Clone: 23E11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: