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Specifications
- Antigen name:Eculizumab
- Clonality:Monoclonal
- Clone:13F5
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Size:40 μg
- Concentration:Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml
- Immunogen:Eculizumab
- Storage buffer:This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide
- Storage temperature:The lyophilized product remains stable up to 1 year at −20 °C from date of receipt. Upon reconstitution, it can be stored for 2 - 3 weeks at 2 - 8 °C or for up to 12 months at −20 °C or below. Avoid repeated freezing and thawing cycles
- Form:Lyophilized
- Cross adsorption:No
- Cat. no.:77007-624
- Packaging:Vial
Specifications
About this item
Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5 or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.Anti-Eculizumab Antibody (13F5), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with eculizumab.
- High specificity
- High affinity
- High stability
GenScript has developed a broad range of off-the-shelf anti-idiotype antibodies against blockbuster drugs to help accelerate your research of biosimilars.
Type:
Antigen: Eculizumab
Clonality: Monoclonal
Clone: 13F5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: