What does CRISPR do?

• Interactive modeling
• How CRISPR was discovered and what it does
• Reusable

Discover how bacteria remember past viral infections and activate their CRISPR systems to search for and destroy the remembered virus’ DNA - preventing infection. This introduction to CRISPR biology will prepare your students to use making the cut with CRISPR-Cas9 and understand how the Cas9 protein works.

With the CRISPR Adaptive Immunity Kit's engaging foam pieces, your students can:
Build the bacteria’s CRISPR array which includes Cas9, trace, spacer and repeats.
Detect the presence of viral double-stranded DNA.
Integrate a short fragment of this viral genome into the bacteria’s CRISPR array.
Express the CRISPR array to create the Cas9 proteins and the guide RNA.