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For the quantification of 15(S)-HETE in urine, plasma, serum, whole blood, and other sample matrices.
- Detect 15(S)-HETE, a product of 15-lipoxygenase treatment of arachidonic acid
- Assay 24 samples in triplicate or 36 samples in duplicate
- Measure 15(S)-HETE levels down to 170 pg/ml
- Read: Colorimetric at 405 to 420 nm
15(S)-HETE is produced from arachidonic acid by the enzyme 15-LO. In humans it is formed primarily in the respiratory epithelium, leukocytes, and reticulocytes. It may contribute to allergic rhinitis, has anti-inflammatory properties, and acts as a vasoconstrictor.
This assay is very specific for 15(S)-HETE, showing very low crossreactivity to other HETEs.
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