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Spécifications
- Antibody type:Primary
- Antigen name:Interferon gamma
- Clonality:Monoclonal
- Clone:4S.B3
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Antigen symbol:IFNG
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Size:100 μg
- Form:liquid
- Antigen synonyms:Type II interferon|T cell interferon|Interferon-g|Macrophage-activating factor (MAF)|IFNg|IFN-g|Interferon-γ|Immune interferon
- Cat. no.:75843-458
- Supplier No.:80811-77-100
Spécifications
A propos de cet article
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells. The biological activity of IFN-γ is not affected by glycosylation.
Type: Primary
Antigen: IFNG
Clonality: Monoclonal
Clone: 4S.B3
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human