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Spécifications
- Antibody type:Primary
- Antigen name:Foxp3
- Clonality:Monoclonal
- Clone:MF23
- Host:Rat
- Isotype:IgG2b
- Reactivity:Mouse
- Antigen symbol:Foxp3
- Conjugation:PE (Phycoerythrin)
- Flow cytometry:Yes
- Size:25 μg
- Form:liquid
- Antigen synonyms:Zinc finger protein JM2|JM2|Forkhead box protein P3|Scurfin|IPEX
- Cat. no.:75842-648
- Supplier No.:83812-60-25
Spécifications
A propos de cet article
The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression. Mutations of Foxp3 result in the “scurfy†mice phenotype. It is reported that the MF23 antibody recognizes an epitope between 1-87 amino acids in the N-terminal domain of mouse Foxp3.
Type: Primary
Antigen: Foxp3
Clonality: Monoclonal
Clone: MF23
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse