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- Antibody type:Primary
- Antigen name:Cluster of Differentiation 8a
- Antigen symbol:CD8a
- Clonality:Monoclonal
- Clone:OKT8
- Conjugation:PE (Phycoerythrin)-Cy7®
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG2a
- Reactivity:Human
- Size:100 tests
- Antigen synonyms:T8|CD8 alpha|Ly-2|Lyt-2|Ly-35|Ly-B
- Form:liquid
- Cat. no.:75842-096
- Supplier No.:10121-77-100
The OKT8 monoclonal antibody specifically reacts with human CD8α molecule, a tyPEI transmembrane glycoprotein of 32-34 kDa. CD8α is a member of the Ig superfamily, expressed as a homodimer (CD8αα) or as a heterodimer (CD8αβ). CD8+ αβ T lymphocytes express both CD8αα and CD8αβ, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes.OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.
Type: Primary
Antigen: CD8a
Clonality: Monoclonal
Clone: OKT8
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human