Human Synthetic DCD-1L Trifluoroacetate
# de catalogue H-7316.0500BA
Fournisseur: Bachem Americas
Numéro CAS:
Spécifications
- Protein/peptide type:Synthetic
- Species:Human
- CAS No.:478898-18-9
- Size:0.5 mg
- Storage conditions:–20 ± 5 °C
- Protein/peptide name:DCD-1L Trifluoroacetate
- Molecular weight:4818.5 g/mol
- Sequence:SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
- Molecular formula:C₂₁₀H₃₅₉N₅₇O₇₁
- Cat. no.:H-7316.0500BA
- Supplier No.:H-7316.0500
Spécifications
A propos de cet article
The protein dermcidin expressed in the sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1).
Dermcidin and naturally occurring fragments as DCD-1L do not perturb membrane permeability and bind to distinct surface molecules. It stimulates keratinocytes to generate cytokines and chemokines such as TNF-α, IL-8, CXCL10, and CCL20.
Sequence: H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH trifluoroacetate salt
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