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Spécifications
- Assay Type:Competitive
- Sensitivity:80% B/B0: 45 pg/mL
- Description:Kit contains: Antibody, Tracer, Standard, Buffers, Reagents, and Plate
- Mid point:50% B/B0: 150 – 250 pg/mL
- Detection range:15.6 - 2000 pg/ml
- Cat. no.:75816-668
- Supplier No.:10004023-96
Spécifications
A propos de cet article
Fast, accurate measurement of TXB2.
- Measure TXB2 in multiple sample types
- Assay 24 samples in triplicate or 36 samples in duplicate
- Measure TXB2 levels down to 45 pg/ml
- Rapid assay; get results in under 4 hours
- Midpoint: 50% B/B0: 150-250 pg/ml
Thromboxane A2 (TXA2), produced from arachidonic acid, causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2 secretion. Cayman’s TXB2 Express ELISA is a competitive assay that provides a rapid, accurate measurement of TXB2 from plasma, urine, and cell culture supernatants.