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Spécifications
- Description:Neuraminidase Assay Kit
- Size:100 assays
- Method:OD570 nm, or FL530/585 nm
- Sample:Biological
- Processing time:60 minutes
- Cat. no.:75878-152
- Supplier No.:ENEU-100
Spécifications
A propos de cet article
For quantitative determination of neuraminidase activity and screen for neuraminidase inhibitor.
- Linear detection range 0.1 to 10 U/L for colorimetric assays and 0.01 to 2 U/L for fluorimetric assays
- Can be readily automated to test thousands of samples per day
Neurominidase (also known as Sialidase) is an enzyme that hydrolyzes terminal sialic acid residues on poly-saccharide chains
BioAssay Systems’ neuraminidase assay measures the sialic acid released by neuraminidase in one step. The change in color intensity of the reaction product at 570nm or fluorescence intensity at λex/em = 530/585nm is directly proportional to neuraminidase activity in the sample.
It is predominantly expressed in microorganisms such as bacteria and viruses. Cleavage of sialic acid residues by neuraminidase is believed to play several roles in infection by influenza viruses. It is thought to assist in the penetration of mucosal linings, the invasion of target cells, the elution of progeny viruses from infected cells, and the prevention of self-aggregation. Thus, neuraminidase is an important target for influenza drug development and simple, direct and automation-ready. Procedures for measuring neuraminidase activity find wide applications in research and drug discovery.