To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Spécifications
- Description:Caspase Assay Kit
- Size:100 assays
- Method:FL400/490 nm
- Sample:Cell and tissue lysate
- Processing time:60 minutes
- Cat. no.:75877-968
- Supplier No.:DCS3-100
Spécifications
A propos de cet article
For quantitative determination of the apoptosis target caspase-3 activity and HTS screen for apoptosis inducers and inhibitors.
- Safe
- Non-radioactive assay
- This homogeneous "mix-incubate-measure" type assay can be readily automated for processing thousands of samples per day
Caspases are members of the aspartate-specific cysteinyl protease family that play a central role in apoptosis
BioAssay Systems’ Caspase-3 Assay Kit provides a convenient means to measure caspase-3 activity in biological samples. In the assay, a specific substrate (N-Ac-DEVD-AFC) is cleaved by active caspase-3, forming a highly fluorescent product. The fluorescence intensity (λex/em = 400/490nm) is proportional to the caspase-3 activity.
Apoptosis is involved in a variety of physiological and pathological events, ranging from normal fetal development to diseases such as cancer, organ failure, and neurodegenerative diseases. Caspase-3 is key biomarker in the assessment of apoptosis and in understanding mechanism of apoptosis induction.
Fournisseur: VWR International
$782.44 to $2,358.46
Fournisseur: Dukal
$14.95 to $179.31
Fournisseur: VWR International
$135.75 to $468.77