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Human Recombinant Mitochondrial Fission 1 (from E. coli)
Human Recombinant Mitochondrial Fission 1 (from E. coli)
# de catalogue 75790-762
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant Mitochondrial Fission 1 (from E. coli)
# de catalogue 75790-762
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    FIS1|TTC11|FIS1 Homolog|Mitochondrial Fission 1 Protein|hFis1|Tetratricopeptide Repeat Protein 11|TPR Repeat Protein 11|CGI-135
  • Protein/peptide name:
    Mitochondrial Fission 1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    15.2 kD
  • Sequence:
    Met1-Gly122
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM Tris, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75790-762
  • Supplier No.:
    92-084

Spécifications

A propos de cet article

Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.

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