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Spécifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Tag sequence:N-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein synonyms:H13|DFF-45|Inhibitor of CAD|DFFA|ICAD|DNA Fragmentation Factor 45 kDa Subunit|DFF1|DNA Fragmentation Factor Subunit Alpha|DFF45
- Protein/peptide name:DFF45
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:38.7 kD
- Sequence:Met1-Thr331
- Formulation:Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:used for biological assays
- Cat. no.:75790-696
- Supplier No.:92-051
Spécifications
A propos de cet article
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
- Fusion-Tag: N-6 His tag
This recombinant protein can be used for biological assays. For research use only.