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Human Recombinant Lecithin-cholesterol acyltransferase (from Cells)
Human Recombinant Lecithin-cholesterol acyltransferase (from Cells)
# de catalogue 75790-224
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant Lecithin-cholesterol acyltransferase (from Cells)
# de catalogue 75790-224
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Enzyme type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Storage conditions:
    Lyophilized protein should be stored at –20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4...7 °C for 2 - 7 days. Aliquots of reconstituted samples are stable at –20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme name:
    Lecithin-cholesterol acyltransferase
  • Enzyme synonyms:
    Phosphatidylcholine-sterol acyltransferase, also named Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase and LACT, is an extracellular cholesterol esterifying enzyme which belongs to the AB hydrolase superfamily., LCAT
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    48.1 kD
  • Sequence:
    Phe25-Glu440
  • Formulation:
    Lyophilized from a 0.2 µm filtered solution of 50 mM Acetate Buffer pH-4.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75790-224
  • Supplier No.:
    91-786

Spécifications

A propos de cet article

Lipase family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

The gene encoding this protein is expressed mainly in brain, liver and testes,followed by secreting into plasma and cerebral spinal fluid. The esterification of cholesterol is required for cholesterol transport. LCAT is a central enzyme in the extracellular metabolism of plasma lipoproteins. Defects in LCAT are the cause of lecithin-cholesterol acyltransferase deficiency (LCATD) and a cause of fish-eye disease (FED).

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