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Spécifications
- Enzyme type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Storage conditions:Lyophilized protein should be stored at –20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4...7 °C for 2 - 7 days. Aliquots of reconstituted samples are stable at –20 °C for 3 months.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Enzyme name:Aldo-Keto Reductase 1C3
- Enzyme synonyms:Aldo-Keto Reductase Family 1 Member C3, 17-Beta-Hydroxysteroid Dehydrogenase Type 5, 17-Beta-HSD 5, 3-Alpha-HSD Type II Brain, 3-Alpha-Hydroxysteroid Dehydrogenase Type 2, 3-Alpha-HSD Type 2, Chlordecone Reductase Homolog HAKRb, Dihydrodiol Dehydrogenase 3, DD-3, DD3, Dihydrodiol Dehydrogenase Type I, HA1753, Indanol Dehydrogenase, Prostaglandin F Synthase, Testosterone 17-Beta-Dehydrogenase 5, Trans-1, 2-Dihydrobenzene-1, 2-Diol Dehydrogenase, AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:37.8 kD
- Sequence:Met1-Tyr323
- Formulation:Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl,pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
- Cat. no.:75790-080
- Supplier No.:91-710
Spécifications
A propos de cet article
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag
It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.