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Human Recombinant CD3 epsilon (from Cells)
Human Recombinant CD3 epsilon (from Cells)
# de catalogue 75789-708
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant CD3 epsilon (from Cells)
# de catalogue 75789-708
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    T-Cell Surface Antigen T3/Leu-4 Epsilon Chain|CD3e|T3E|T-Cell Surface Glycoprotein CD3 Epsilon Chain
  • Protein/peptide name:
    CD3 epsilon
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    12.79 kD
  • Sequence:
    Asp23-Asp126
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75789-708
  • Supplier No.:
    91-516

Spécifications

A propos de cet article

T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.

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