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Human Recombinant TIMP1 (from Cells)
Human Recombinant TIMP1 (from Cells)
# de catalogue 75789-500
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant TIMP1 (from Cells)
# de catalogue 75789-500
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    Erythroid-Potentiating Activity|Metalloproteinase Inhibitor 1|Tissue Inhibitor of Metalloproteinases 1|CLGI|TIMP1|TIMP|Collagenase Inhibitor|Fibroblast collagenase Inhibitor|EPA|TIMP-1
  • Protein/peptide name:
    TIMP1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    21.75 kD
  • Sequence:
    Cys24-Ala207
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75789-500
  • Supplier No.:
    91-412

Spécifications

A propos de cet article

Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.

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