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Spécifications
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Tag sequence:C-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Endotoxin content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein synonyms:Bone Morphogenetic Protein Receptor Type-2|BMPR-II|PPH1|BMP Type-2 Receptor|Bone Morphogenetic Protein Receptor Type II|BMP Type II Receptor|BMPR-2|BMPR2
- Protein/peptide name:BMP Receptor II
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:15.05 kD
- Sequence:Ser27-Ile151
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
- Cat. no.:75789-242
- Supplier No.:91-283
Spécifications
A propos de cet article
Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.