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Human Recombinant UBE2H (from E. coli)
Human Recombinant UBE2H (from E. coli)
# de catalogue 75789-046
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant UBE2H (from E. coli)
# de catalogue 75789-046
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    N-GST tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    Ubiquitin-Conjugating Enzyme E2-20K|Ubiquitin Carrier Protein H|UbcH2|Ubiquitin-Protein Ligase H|Ubiquitin-Conjugating Enzyme E2 H|UBE2H
  • Protein/peptide name:
    UBE2H
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    47 kD
  • Sequence:
    Met1-Leu183
  • Formulation:
    Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    For Biological assays
  • Cat. no.:
    75789-046
  • Supplier No.:
    91-165

Spécifications

A propos de cet article

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

  • Fusion-Tag: N-GST tag

This recombinant protein can be used for biological assays. For research use only.

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