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Human Recombinant beta-Defensin 4A (from E. coli)
Human Recombinant beta-Defensin 4A (from E. coli)
# de catalogue 75788-936
Fournisseur:  Prosci
Numéro CAS:  
Human Recombinant beta-Defensin 4A (from E. coli)
# de catalogue 75788-936
Fournisseur:  Prosci
Numéro CAS:  
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Spécifications

  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    Beta-Defensin 2|DEFB2|BD-2|Beta 2|DEFB4A|Beta-Defensin 4A|SAP1|hBD-2|DEFB4|Skin-Antimicrobial Peptide 1|DEFB102|Defensin|DEFB4B
  • Protein/peptide name:
    beta-Defensin 4A
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    4.33 kD
  • Sequence:
    Gly24-Pro64
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    For Biological assays
  • Cat. no.:
    75788-936
  • Supplier No.:
    91-110

Spécifications

A propos de cet article

beta -Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 beta -Defensins, which are distinguished from alpha-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. beta -Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.

This recombinant protein can be used for biological assays. For research use only.

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