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Anti-SHC1 Rabbit Polyclonal Antibody
Anti-SHC1 Rabbit Polyclonal Antibody
# de catalogue 10374-140
Fournisseur:  Bioss
Anti-SHC1 Rabbit Polyclonal Antibody
# de catalogue 10374-140
Fournisseur:  Bioss
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Spécifications

  • Antibody type:
    Primary
  • Antigen name:
    SHC-transforming Protein 1
  • Clonality:
    Polyclonal
  • Gene ID:
    6464
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Antigen symbol:
    SHC1
  • Conjugation:
    Unconjugated
  • ImmunoChemistry:
    Yes
  • Size:
    100 µg
  • Western blot:
    Yes
  • Cross adsorption:
    No
  • Form:
    liquid
  • Antigen synonyms:
    SHC|SH2 domain protein C1|FLJ26504|SHC1|p66SHC|Src homology 2 domain-containing-transforming protein C1|SHC-transforming protein 1|p52SHC|p66|SHCA
  • Modification:
    Tyr349
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
  • Storage temperature:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Cat. no.:
    10374-140
  • Supplier No.:
    BS-3411R

Spécifications

A propos de cet article

The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains. The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, both containing a C-terminal SH2 domain. Adjacent to the SH2 region is a glycine and proline rich region. These 2 proteins differ in their N terminals. SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway. The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways.

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: SHC1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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