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Spécifications
- Antibody type:Primary
- Antigen name:Ran-binding Protein 7
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:RANBP7
- Conjugation:HRP (Horseradish Peroxidase)
- ImmunoChemistry:Yes
- Size:100 µL
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:RanBP7.|IPO7_HUMAN|Importin-7|IPO7|RANBP 7|Ran binding protein 7|Imp 7|Importin7|Imp7|Ran-binding protein 7|IPO 7
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10663-616
- Supplier No.:BS-8590R-HRP
Spécifications
A propos de cet article
Importin 7 is a 1,038 amino acid protein encoded by the human gene IPO7. Importin-7 belongs to the importin b family and contains one importin N-terminal domain. Importin-7 functions in nuclear protein import, either by acting as an autonomous nuclear transport receptor or as an adapter-like protein in association with the Importin b subunit KPNB1. Acting autonomously, Importin-7 is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to Importin-7, the Importin-7/substrate complex dissociates and Importin-7 is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. Importin-7 is a nuclear protein that is expressed in most tissues.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: RANBP7
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat