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Spécifications
- Antibody type:Primary
- Antigen name:H2A histone Family, member X
- Clonality:Polyclonal
- Gene ID:3014
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat
- Antigen symbol:H2AFX
- Conjugation:Cy7®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:H2A histone family member X|H2AFX anitbody|H2A.x|gamma-H2AX|histone H2A|H2AX
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:90-130/143
- Purification:Purified by Protein A
- Cat. no.:10662-552
- Supplier No.:BS-8571R-CY7
Spécifications
A propos de cet article
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: Histone H2A.X Ubiquityl Lys119
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat