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Spécifications
- Antibody type:Primary
- Antigen name:Ubiquitin conjugating enzyme E2A
- Clonality:Polyclonal
- Gene ID:7319
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:UBE2A
- Conjugation:Cy5.5®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:HHR6A|UBC2|MRXSN|MRXS30|RAD6A
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10483-154
- Supplier No.:BS-8375R-CY5.5
Spécifications
A propos de cet article
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (Ubiquitin-conjugating enzyme E2 A) and UBE2B (Ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to postreplication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: UBE2A
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat