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Spécifications
- Antibody type:Primary
- Antigen name:Bactericidal/permeability-increasing Protein
- Clonality:Polyclonal
- Gene ID:671
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:BPI
- Conjugation:Cy7®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:CAP 57|bactericidal/permeability-increasing protein|BPI|Bactericidal permeability-increasing protein|BPI_HUMAN.
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10402-708
- Supplier No.:BS-4292R-CY7
Spécifications
A propos de cet article
The antimicrobial protein Bactericidal Permeability Increasing protein (BPI) is a 55 kDa protein found in the primary granules of polymorhonuclear leukocytes (PMN). The cytotoxicity action of BPI is limited to gram negative bacteria, reflecting the high affinity of BPI for bacterial LPS. Binding of BPI to live bacteria via LPS causes anti-infective activites: 1) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes, 2) neutralization of gram-negative bacterial LPS, 3) opsonization of bacteria to enhance phagocytosis by neutrophils.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: BPI
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human