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Spécifications
- Antibody type:Primary
- Antigen name:Glucagon Receptor
- Clonality:Polyclonal
- Gene ID:2642
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:GCGR
- Conjugation:Alexa Fluor® 488
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:GGR|GL-R
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:26-70/477
- Purification:Purified by Protein A
- Cat. no.:10395-364
- Supplier No.:BS-3945R-A488
Spécifications
A propos de cet article
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: Glucagon Receptor
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat