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Anti-CUBN Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Anti-CUBN Rabbit Polyclonal Antibody (Alexa Fluor® 647)
# de catalogue 10389-594
Fournisseur:  Bioss
Anti-CUBN Rabbit Polyclonal Antibody (Alexa Fluor® 647)
# de catalogue 10389-594
Fournisseur:  Bioss
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Spécifications

  • Antibody type:
    Primary
  • Antigen name:
    Cubilin
  • Clonality:
    Polyclonal
  • Gene ID:
    8029
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Antigen symbol:
    CUBN
  • Conjugation:
    Alexa Fluor® 647
  • ImmunoChemistry:
    Yes
  • Size:
    100 µL
  • Cross adsorption:
    No
  • Form:
    liquid
  • Antigen synonyms:
    GP280|MGA1|IFCR|gp280
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Storage temperature:
    Store at 4°C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Immunogen:
    50-90/3623
  • Purification:
    Purified by Protein A
  • Cat. no.:
    10389-594
  • Supplier No.:
    BS-3901R-A647

Spécifications

A propos de cet article

Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CUBN
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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