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Spécifications
- Antibody type:Primary
- Antigen name:Nucleoporin p63
- Clonality:Polyclonal
- Gene ID:8626
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:p63
- Conjugation:Cy5®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:p51|Tumor protein p73-like|p73L|Keratinocyte transcription factor KET|P73L|TP63|Tumor protein 63|KET|CUSP|p40|Chronic ulcerative stomatitis protein|Transformation-related protein 63|TP73L|P63|P73H
- Modification:phospho-Ser455
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10386-716
- Supplier No.:BS-3715R-CY5
Spécifications
A propos de cet article
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008].
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: p63
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human