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Spécifications
- Antibody type:Primary
- Antigen name:SMAD Family Member 2 And 3
- Clonality:Polyclonal
- Gene ID:4087,4088
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:SMAD2 + SMAD3
- Conjugation:Cy5®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Mothers against decapentaplegic homolog 2|SMAD2|JV15-2|hMAD-2|SMAD family member 2|MAD homolog 2|SMAD3|Mothers against DPP homolog 3|Mad2|SMAD 3|Mothers against decapentaplegic homolog 3|MADH2|SMAD family member 3|hSMAD3|Mad3|hMAD-3|MAD homolog 3|Smad3|Mothers against DPP homolog 2|MADH3
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:30-80/467
- Purification:Purified by Protein A
- Cat. no.:10369-700
- Supplier No.:BS-3484R-CY5
Spécifications
A propos de cet article
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: SMAD2 + SMAD3
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat