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Spécifications
- Antibody type:Primary
- Antigen name:Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 1
- Clonality:Polyclonal
- Gene ID:4790
- Host:Rabbit
- Isotype:IgG
- Reactivity:Rat
- Antigen symbol:NFKB1
- Conjugation:Alexa Fluor® 555
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:NFkappaB|EBP-1|p50|NFKB-p50|NFKB-p105|NF-kB1|NF-kappaB|p105|KBF1|NF-kappa-B
- Modification:phospho-Ser927
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10373-996
- Supplier No.:BS-3300R-A555
Spécifications
A propos de cet article
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: NFKB1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat