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Spécifications
- Antibody type:Primary
- Antigen name:NF-kappa-B essential modulator
- Clonality:Polyclonal
- Gene ID:8517
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:IKBKG
- Conjugation:FITC (Fluorescein Isothiocyanate)
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:NEMO|IPD2|IMD33|FIP3|IKK-gamma|Fip3p|ZC2HC9|IP|AMCBX1|IP1|FIP-3|IP2
- Modification:phospho-Ser31
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10354-606
- Supplier No.:BS-3228R-FITC
Spécifications
A propos de cet article
Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: IKBKG
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human