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Spécifications
- Antibody type:Primary
- Antigen name:Interleukin 17C
- Clonality:Polyclonal
- Gene ID:27189
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:IL17C
- Conjugation:Unconjugated
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- Size:100 µL
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:interleukin-17C|IL-21|IL-17C|cytokine CX2|CX2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:90-130/197
- Purification:Purified by Protein A
- Cat. no.:10342-690
- Supplier No.:BS-2611R
Spécifications
A propos de cet article
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Recommended Dilutions: Western Blot: 1:100-1000; Flow Cytometry: 1:20-100; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: IL17C
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat