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Spécifications
- Antibody type:Primary
- Antigen name:Caspase 3
- Clonality:Polyclonal
- Gene ID:25402
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:CASP3
- Conjugation:Cy5.5®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Caspase-3 subunit p12|Protein Yama|Cysteine protease CPP32|3.4.22.56|CASP-3|Cysteine protease CPP32 Caspase-3|Apopain|Caspase-3 subunit p17|Cpp32|SCA-1|CPP-32|SREBP cleavage activity 1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:1-45/277
- Purification:Purified by Protein A
- Cat. no.:10342-270
- Supplier No.:BS-2593R-CY5.5
Spécifications
A propos de cet article
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CASP3
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human, Mouse, Rat