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Spécifications
- Antibody type:Primary
- Antigen name:Caspase 9
- Clonality:Polyclonal
- Gene ID:842
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CASP9
- Conjugation:Cy3®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:EC 3.4.22.62|ICE-like apoptotic protease 6,ICE-LAP6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3|Apaf-3|CASP-9
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:280-330/416
- Purification:Purified by Protein A
- Cat. no.:10229-992
- Supplier No.:BS-0050R-CY3
Spécifications
A propos de cet article
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: CASP9
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human