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Spécifications
- Antibody type:Primary
- Antigen name:Cytochrome c, somatic
- Clonality:Polyclonal
- Gene ID:54205
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:CYCS
- Conjugation:Alexa Fluor® 488
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:CYCSA|HCS|THC4|CYC
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:50-89/105
- Purification:Purified by Protein A
- Cat. no.:10229-200
- Supplier No.:BS-0013R-A488
Spécifications
A propos de cet article
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Recommended Dilutions: IF(IHC-P): 1:50-200; IF(ICC)(1:50-200
Type: Primary
Antigen: CYCS
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype:
Reactivity: