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Spécifications
- Antibody type:Primary
- Antigen name:praja ring finger 1, E3 ubiquitin protein ligase
- Clonality:Polyclonal
- Gene ID:Q8NG27
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PJA1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the N-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:PJA1
- Storage buffer:PJA1 antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 71 kDa Observed: 71 kDa
- Storage temperature:PJA1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:PJA1 antibody was raised against a 19 amino acid peptide near the amino terminus of human PJA1. The immunogen is located within amino acids 50 - 100 of PJA1.
- Purification:PJA1 antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-036
- Supplier No.:8069_S
Spécifications
A propos de cet article
Ubiquitinization is an important cellular degradation process requiring sequential reactions that are mediated by three enzymes: E1, E2 and E3. PJA1, also known as Praja1 and RING finger protein 70, is a 643 amino acid E2-dependent E3-ubiquitin ligase that is abundantly expressed in the brain. Through interaction and activation with the E2-ubiquitin ligase UBC4, PJA1 mediates substrate-specific ubiquitination via its RING finger domain and facilitates ubiquitination. Overexpression of PJA1 in gastrointestinal cancers suggests that it may be responsible for the degradation of some anti-oncogenic proteins.
Type: Primary
Antigen: PJA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat