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Spécifications
- Antibody type:Primary
- Antigen name:LIM domain and actin binding 1
- Clonality:Polyclonal
- Gene ID:Q9UHB6
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:LIMA1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the N-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:LIMA1
- Storage buffer:LIMA1 antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 50, 66, 84 kDa Observed: 65 kDa
- Storage temperature:LIMA1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:LIMA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human LIMA1. The immunogen is located within amino acids 230 - 280 of LIMA1.
- Purification:LIMA1 antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-026
- Supplier No.:8053_S
Spécifications
A propos de cet article
The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines. LIMA1 is also a key molecule linking the cadherin-catenin complex to the actin cytoskeleton. Recent studies have shown that EGF activates ERK1/2-dependent phosphorylation, ubiquitination and degradation of LIMA1, leading to increased invasiveness and metastasis of metastatic prostate cancer models.
Type: Primary
Antigen: LIMA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human