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Spécifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.02 mg
- Tag sequence:Tag free
- Biological activity:Corresponding to a specific activity of 20000 IU/mg. The ED50 as determined by the cytolysis of MC3T3-E1 cells is <50 ng/mL.
- Protein synonyms:BMP2A|BMP2
- Protein/peptide name:BMF2
- Purity:>92% as determined by SDS-PAGE.
- Molecular weight:13 kDa
- Formulation:Lyophilized, 0.1M acetic acid, pH2.0
- Tested applications:Western Blot
- Cat. no.:10797-074
- Supplier No.:96-065
Spécifications
A propos de cet article
Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.