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Spécifications
- Antibody type:Primary
- Antigen name:Synaptic Ras GTPase-activating protein 1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:SYNGAP
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:ras GTPase-activating protein SynGAP|SYNGAP1|MRD5|DKFZp761G1421|synaptic Ras GTPase activating protein 1 homolog|synaptic Ras GTPase activating protein 1|KIAA1938|neuronal RasGAP|RASA5|RASA1
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Peptide
- Purification:Antigen affinity Purification
- Supplier No.:19739-1-AP
Spécifications
A propos de cet article
SYNGAP1, also named as KIAA1938, is the major constituent of the PSD essential for postsynaptic signaling. It’s an inhibitory regulator of the Ras-cAMP pathway. SYNGAP1 is a member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. SYNGAP1 regulates AMPAR-mediated miniature excitatory postsynaptic currents. SYNGAP1 may be involved in certain forms of brain injury, leading to long-term learning and memory deficits Defects in SYNGAP1 are the cause of mental retardation autosomal dominant type 5 (MRD5).
Western Blot: Mouse Brain Tissue, 1:1000-1:10000; IF: HepG2, 1:10-1:100
Type: Primary
Antigen: SYNGAP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat