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Spécifications
- Antibody type:Primary
- Antigen name:Myocyte Enhancer Factor 2C
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:MEF2C
- Conjugation:Unconjugated
- ELISA:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:MADS box transcription enhancer factor 2 polypeptide C myocyte enhancer factor 2C|Myocyte enhancer factor 2C|Similar to MADS box transcription enhancer factor 2 polypeptide C|MEF2Cphospho S387|MEF2C_HUMAN.|Myocyte specic enhancer factor 2C
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10081-614
- Supplier No.:16953-1-AP
Spécifications
A propos de cet article
MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. This antibody is a rabbit polyclonal antibody raised against an internal region of human MEF2C.
Western Blot: Human Heart Tissue, 1:500-1:5000
Type: Primary
Antigen: MEF2C
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat