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Specifications
- Antibody type:Primary
- Antigen name:Mitotic checkpoint serine/threonine-protein kinase BUB1
- Antigen symbol:BubR1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Size:150 µL
- Antigen synonyms:mitotic checkpoint kinase MAD3L|MAD3L|MAD3/BUB1-related protein kinase|hBUBR1|SSK1|mitotic checkpoint serine/threonine-protein kinase BUB1 beta|BUBR1|BUB1beta|Bub1A
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Cat. no.:10083-732
- Supplier No.:11504-2-AP
Specifications
About this item
BUB1B(Mitotic checkpoint serine/threonine-protein kinase BUB1 beta) is lalso named as BUBR1, MAD3L, SSK1 and belongs to the BUB1 subfamily. Human BUB1B is a 120 kDa protein that plays a central role in the spindle assembly checkpoint (SAC), the evolutionary conserved and self-regulatory system of higher organisms that monitors and repairs defects in chromosome segregation in mitotic cells. In addition to phosphorylation, BUB1B is also subjected to posttranslational modifications including acetylation. Defects in BUB1B are the cause of premature chromatid separation trait (PCS) and mosaic variegated aneuploidy syndrome type 1 (MVA1).
Western Blot: Mouse Testis Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:10-1:100
Type: Primary
Antigen: BubR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse