A propos de cet article
The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
Type: Primary
Antigen: CD178 (Fas ligand)
Clonality:
Clone: NOK-1
Conjugation: APC
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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Spécifications
- Catalog No:
- 10141-008
- 10141-006
- Antigen name:
- Fas Ligand
- Fas Ligand
- Antibody type:
- Primary
- Primary
- Clone:
- NOK-1
- NOK-1
- Host:
- Mouse
- Mouse
- Gene ID:
- 356
- 356
- Isotype:
- IgG1
- IgG1
- Neutralisation:
- Yes
- Yes