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Spécifications
- Antibody type:Primary
- Antigen name:Killer cell lectin-like receptor subfamily B, member 1
- Clonality:Monoclonal
- Clone:HP-3G10
- Gene ID:3820
- Host:Mouse
- Isotype:IgG1
- Neutralisation:Yes
- Reactivity:Baboon,Rhesus monkey,Chimpanzee,Human
- Antigen symbol:KLRB1
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Size:100 µg
- Western blot:Yes
- Antigen synonyms:NKRP1A|hNKR-P1A|NKR-P1A|NKR-P1|NKR|CLEC5B|CD161
- Storage temperature:Store undiluted at 2-8°C, protect from light, do not freeze.
- Tested applications:Flow Cytometry
- Cat. no.:10051-716
- Supplier No.:70-1619-U100
Spécifications
A propos de cet article
The HP-3G10 antibody is specific for human CD161, also known as NKR-P1A, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer which is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.
The HP-3G10 antibody may be used for flow cytometric analysis of CD161 on NK and NKT cells, as well as on various T cell subsets. The antibody is also reported to be cross-reactive with Baboon, Chimpanzee and Rhesus CD161.
Type: Primary
Antigen: KLRB1
Clonality: Monoclonal
Clone: HP-3G10
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Chimpanzee, Baboon, Rhesus