A propos de cet article
The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Type: Primary
Antigen: Foxp3
Clonality:
Clone: MF23
Conjugation: APC
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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Spécifications
- Catalog No:
- 10140-998
- 10141-000
- Antigen name:
- Forkhead Box P3
- Forkhead Box P3
- Antibody type:
- Primary
- Primary
- Clone:
- MF23
- MF23
- Host:
- Rat
- Rat
- Gene ID:
- 20371
- 20371
- Isotype:
- IgG2b
- IgG2b
- Neutralisation:
- Yes
- Yes