A propos de cet article
The 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.
The 1D3 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
Type: Primary
Antigen: CD19
Clonality: Monoclonal
Clone: 1D3
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype:
Reactivity: Mouse
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Spécifications
- Catalog No:
- 10050-462
- 10050-464
- Antigen name:
- CD19 molecule
- CD19 molecule
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- 1D3
- 1D3
- Host:
- Rat
- Rat
- Gene ID:
- 12478
- 12478
- Isotype:
- IgG2a
- IgG2a